Custom Conjugation - Columbia Biosciences

Why Choose Columbia Biosciences for Your Next Custom Conjugation?

Wide range of experience including fluorescent dyes, enzymes, proteins, haptens, and PEG – See list of common labels
Flexible – we provide conjugation services for both research and commercial applications
Rapid turnaround time – 10-14 days, expedited 7 day service also available
Experienced team – over 20 years of antibody and protein conjugation experience
Certificate of Analysis for every conjugate includes concentration, F/P ratio and fluorometry
Scale up capabilities – microgram to gram scale
Conjugation service provider to most of the largest pharmaceutical companies

For a flyer you can download and print, click here.

Please fill out the form below to request a quote. Please note the form may take a moment to load. You can reach this page by going to www.customconjugation.com

Custom Conjugation - Request for Quote

RFQ Number

Name(Required)

First Last

Organization(Required)

Email(Required)

Additional Email

Optional - An additional email address where the quote should be sent.

Phone

Shipping Address(Required)

Street Address Address Line 2 City State / Province / Region ZIP / Postal Code Country

DELIVERY TIME

DEFAULT: 2 weeks

Expedited (7 days)

APPLICATION(Required)

OTHER APPLICATION

Please specify:

SPECIAL ANALYSIS

Additional services:

CONJUGATION # 1

LABEL # 1(Required)

Other Label # 1(Required)

MATERIAL # 1(Required)

Name or Codename of Antibody or Protein. Please provide an identification that will match how the material is labeled on the vial(s).

AMOUNT (Material # 1)(Required)

Amount of material to be labeled (mg) @ concentration (mg/mL) (if known)

TYPE (Material # 1)(Required)

e.g. protein, antibody, IgG and subclasses, IgM, drug, PEG, biotin, polystyrene bead, surface

MOLECULAR WEIGHT (Material # 1)

kDa

EXTINCTION COEFFICIENT (Material # 1)

Please provide the molar extinction coefficient (at 280nm) or the AU per mg (at 280nm)

SOURCE (Material # 1)

DEFAULT: Customer will provide material.

Columbia Biosciences will source material to be labeled.

SPECIAL HANDLING (Material # 1)

CONJUGATION SITE (Material # 1)

DEFAULT: Lysine / Amine site

Cysteine site

Glycan site

Reduced antibody Fc hinge

To be discussed

STARTING BUFFER (Material # 1)

Contains carrier proteins (will reduce yield)

Azide free

Endotoxin free

Other

OTHER STARTING BUFFER (Material # 1)

FINAL BUFFER REQUIREMENT (Material # 1)

Azide free

Endotoxin free

Other

OTHER FINAL BUFFER REQUIREMENT (Material # 1)

Please provide other final buffer requirements (if any).

FINAL FORMAT (Material # 1)

DEFAULT: Liquid

Lyophilized

Frozen

CUSTOM ALIQUOTING (Material # 1)

DEFAULT: Vialed in bulk. For custom aliquoting, please specify aliquot volume and concentration below.

SHIPPING CONDITIONS (Material # 1)

DEFAULT: Ship on Blue Ice. Please check box if necessary to ship the finished conjugate on dry ice.

Ship on Dry Ice.

STABILITY INFO (Material # 1)

Are there any specific requirements for the stability of your material that need to be taken into account during conjugation? (i.e. ionic strength, pH, temperature)?

COMMENTS (Material # 1)

Please tell us any additional requirements for conjugation # 1.

CONJUGATION # 2

LABEL # 2

Other Label # 2(Required)

Please specify Label # 2

MATERIAL # 2(Required)

Name or Codename of Antibody or Protein: Please provide an identification that will match how the material is labeled on the vial(s).

AMOUNT (Material # 2)(Required)

Amount of material to be labeled (mg)@ concentration (mg/mL) (if known)

TYPE (Material # 2)(Required)

e.g. protein, antibody, IgG and subclasses, IgM, drug, PEG, biotin, polystyrene bead, surface

MOLECULAR WEIGHT (Material # 2)

kDa

EXTINCTION COEFFICIENT (Material # 2)

Please provide the molar extinction coefficient (at 280nm) or the AU per mg (at 280nm)

SOURCE (Material # 2)

DEFAULT: Customer will provide material.

Columbia Biosciences will source material to be labeled.

SPECIAL HANDLING (Material # 2)

CONJUGATION SITE (Material # 2)

DEFAULT: Lysine / Amine site

Cysteine site

Glycan site

Reduced antibody Fc hinge

To be discussed

STARTING BUFFER (Material # 2)

Contains carrier proteins (will reduce yield)

Azide free

Endotoxin free

Other

OTHER STARTING BUFFER (Material # 2)

FINAL BUFFER REQUIREMENT (Material # 2)

Azide free

Endotoxin free

Other

OTHER FINAL BUFFER REQUIREMENT (Material # 2)

Please provide other final buffer requirements.

FINAL FORMAT (Material # 2)

DEFAULT: Liquid

Lyophilized

Frozen

CUSTOM ALIQUOTING (Material # 2)

DEFAULT: Vialed in bulk. For custom aliquoting, please specify aliquot volume and concentration.

SHIPPING CONDITIONS (Material # 2)

DEFAULT: Ship on Blue Ice. Please check box if necessary to ship the finished conjugate on dry ice.

Ship on Dry Ice.

STABILITY INFO (Material # 2)

Are there any specific requirements for the stability of your protein that need to be taken into account during conjugation? (i.e. ionic strength, pH, temperature)?

COMMENTS (Material # 2)

Please tell us any additional requirements for conjugation # 2.

CONJUGATION # 3

LABEL # 3

Other Label # 3

Please specify Label # 3

MATERIAL # 3(Required)

Name or Codename of Antibody or Protein: Please provide an identification that will match how the material is labeled on the vial(s).

AMOUNT (Material # 3)(Required)

Amount of material to be labeled (mg)@ concentration (mg/mL) (if known)

TYPE (Material # 3)(Required)

e.g. protein, antibody, IgG and subclasses, IgM, drug, PEG, biotin, polystyrene bead, surface

MOLECULAR WEIGHT (Material # 3)

kDa

EXTINCTION COEFFICIENT (Material # 3)

Please provide the molar extinction coefficient (at 280nm) or the AU per mg (at 280nm)

SOURCE (Material # 3)

DEFAULT: Customer will provide material.

Columbia Biosciences will source material to be labeled.

SPECIAL HANDLING (Material # 3)

CONJUGATION SITE (Material # 3)

DEFAULT: Lysine / Amine site

Cysteine site

Glycan site

Reduced antibody Fc hinge

To be discussed

STARTING BUFFER (Material # 3)

Contains carrier proteins (will reduce yield)

Azide free

Endotoxin free

Other

OTHER STARTING BUFFER (Material # 3)

FINAL BUFFER REQUIREMENT (Material # 3)

Azide free

Endotoxin free

Other

OTHER FINAL BUFFER REQUIREMENT (Material # 3)

Please provide other final buffer requirements (if any).

FINAL FORMAT (Material # 3)

DEFAULT: Liquid

Lyophilized

Frozen

CUSTOM ALIQUOTING (Material # 3)

DEFAULT: Vialed in bulk. For custom aliquoting, please specify aliquot volume and concentration below.

SHIPPING CONDITIONS (Material # 3)

DEFAULT: Ship on Blue Ice. Please check box if necessary to ship the finished conjugate on dry ice.

Ship on Dry Ice.

STABILITY INFO (Material # 3)

Are there any specific requirements for the stability of your material that need to be taken into account during conjugation? (i.e. ionic strength, pH, temperature)?

COMMENTS (Material # 3)

Please tell us any additional requirements for conjugation # 3.

CONJUGATION # 4

LABEL # 4

Other Label # 4

Please specify Label # 4

MATERIAL # 4(Required)

Name or Codename of Antibody or Protein: Please provide an identification that will match how the material is labeled on the vial(s).

AMOUNT (Material # 4)(Required)

Amount of material to be labeled (mg)@ concentration (mg/mL) (if known)

TYPE (Material # 4)(Required)

e.g. protein, antibody, IgG and subclasses, IgM, drug, PEG, biotin, polystyrene bead, surface

MOLECULAR WEIGHT (Material # 4)

kDa

EXTINCTION COEFFICIENT (Material # 4)

Please provide the molar extinction coefficient (at 280nm) or the AU per mg (at 280nm)

SOURCE (Material # 4)

DEFAULT: Customer will provide material.

Columbia Biosciences will source material to be labeled.

SPECIAL HANDLING (Material # 4)

CONJUGATION SITE (Material # 4)

DEFAULT: Lysine / Amine site

Cysteine site

Glycan site

Reduced antibody Fc hinge

To be discussed

STARTING BUFFER (Material # 4)

Contains carrier proteins (will reduce yield)

Azide free

Endotoxin free

Other

OTHER STARTING BUFFER (Material # 4)

FINAL BUFFER REQUIREMENT (Material # 4)

Azide free

Endotoxin free

Other

OTHER FINAL BUFFER REQUIREMENT (Material # 4)

FINAL FORMAT (Material # 4)

DEFAULT: Liquid

Lyophilized

Frozen

CUSTOM ALIQUOTING (Material # 4)

DEFAULT: Vialed in bulk. For custom aliquoting, please specify aliquot volume and concentration.

SHIPPING CONDITIONS (Material # 4)

DEFAULT: Ship on Blue Ice. Please check box if necessary to ship the finished conjugate on dry ice.

Ship on Dry Ice.

STABILITY INFO (Material # 4)

Are there any specific requirements for the stability of your material that need to be taken into account during conjugation? (i.e. ionic strength, pH, temperature)?

COMMENTS (Material # 4)

Please tell us any additional requirements for conjugation # 4.

CONJUGATION # 5

LABEL # 5

Other Label # 5

MATERIAL # 5(Required)

Name or Codename of Antibody or Protein. Please provide an identification that will match how the material is labeled on the vial(s).

AMOUNT (Material # 5)(Required)

Amount of material to be labeled (mg)@ concentration (mg/mL) (if known)

TYPE (Material # 5)(Required)

e.g. protein, antibody, IgG and subclasses, IgM, drug, PEG, biotin, polystyrene bead, surface

MOLECULAR WEIGHT (Material # 5)

kDa

EXTINCTION COEFFICIENT (Material # 5)

Please provide the molar extinction coefficient (at 280nm) or the AU per mg (at 280nm)

SOURCE (Material # 5)

DEFAULT: Customer will provide material.

Columbia Biosciences will source material to be labeled.

SPECIAL HANDLING (Material # 5)

CONJUGATION SITE (Material # 5)

DEFAULT: Lysine / Amine site

Cysteine site

Glycan site

Reduced antibody Fc hinge

To be discussed

STARTING BUFFER (Material # 5)

Contains carrier proteins (will reduce yield)

Azide free

Endotoxin free

Other

OTHER STARTING BUFFER (Material # 5)

FINAL BUFFER REQUIREMENT (Material # 5)

Azide free

Endotoxin free

Other

OTHER FINAL BUFFER REQUIREMENT (Material # 5)

Please provide other final buffer requirements.

FINAL FORMAT (Material # 5)

DEFAULT: Liquid

Lyophilized

Frozen

CUSTOM ALIQUOTING (Material # 5)

DEFAULT: Vial in bulk. For custom aliquoting, please specify aliquot volume and concentration.

SHIPPING CONDITIONS (Material # 5)

DEFAULT: Ship on Blue Ice. Please check box if necessary to ship the finished conjugate on dry ice.

Ship on Dry Ice.

STABILITY INFO (Material # 5)

Are there any specific requirements for the stability of your material that need to be taken into account during conjugation? (i.e. ionic strength, pH, temperature)?

COMMENTS (Material # 5)

Please tell us any additional requirements for conjugation # 5.

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