HTS is the process of testing a large number of diverse chemical structures against disease targets to identify ‘hits’. HTS is now widely used by pharmaceutical and biotech companies and academic institutions for drug discovery, target validation and the identification of genes or proteins that modulate a particular biological pathway.
Columbia Biosciences manufactures and sells donor and acceptor fluorophore conjugates. Our products includes a large variety of anti-epitope tag and anti-species antibodies and streptavidin conjugates for TR-FRET (LANCE®, HTRF®). The conjugates labeled with SureLight™ APC or Dylight® 650 can be paired with Europium cryptate and chelate based donors. PE or Dylight® 550 conjugates can be paired with Terbium chelate based donors.