Immunoassays based on Luminex xMAP technology enable simultaneous detection and quantitation of multiple secreted proteins (cytokines, chemokines, growth factors, etc.) and have been invaluable for the comprehensive study of biological systems. This high-throughput technology produces results comparable to ELISA but with greater efficiency, speed and dynamic range.

Columbia Biosciences developed and sells two versions of its SureLight streptavidin-R-phycoerythrin (SAPE) for use in Luminex kits: SureLight™ Polymeric Streptavidin R-Phycoerythrin (high-intensity) which is suited for applications where small amounts of antigens are available and SureLight™ Streptavidin R-Phycoerythrin (standard-intensity) which is more suitable for moderate sensitivity assays.